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Our laboratory is focused on characterizing the mechanisms by which anxiety alters the processing of threats and punishments in a way that enhances the likelihood of avoidance and behavioral inhibition. Clinically, our work promises to enhance our understanding of how emotional traits and states modulate risk, facilitate the discovery of novel endophenotypes and biomarkers, and set the stage for developing improved interventions.


Alexander J. Shackman, Ph.D.
Lab Director
University of Maryland
3123G Biology-Psychology Building
College Park, MD 20742-4411